energenesis

The most powerful mitochondria and energy support supplement ever created.

Energenesis
Energenesis

The most powerful mitochondria and energy support supplement ever created.

The Big Key to REAL Energy Enhancement Isn't Sugar and Stimulants - it's Optimizing Your Mitochondria

Virtually all of the energy that powers all the trillions of cells in your body comes from your mitochondria.

Watch the video below for an in-depth explanation:

Mitochondria

The Powerhouses of the cell.

They are the absolute most critical physiological system involved in our energy levels. If you are dealing with fatigue, that is almost certainly a sure sign that your mitochondria are not functioning well. Here’s the problem: As you age, your mitochondria become damaged and dysfunctional. And they even shrink in size

Think of how a muscle shrinks or atrophies if it’s in a cast – the same thing happens to our mitochondria, our energy generators over time. Research has shown that for most people, from the age of 20-40, their mitochondrial capacity (the ability of our cells to produce energy) decreases by HALF. And then, from 40-70, it decreases by another HALF!

Up to Age 20
Age 20 - 40
Age 40 - 70

As a result, the energy your mitochondria produce naturally decreases over time, reducing your health and longevity — and ultimately, causing fatigue.

On top of that, stressors in our life — from psychological stress, to environmental toxins (like heavy metals and air pollutants), to a poor diet, to poor gut health, to chronic inflammation — all-cause mitochondrial damage, dysfunction and shut down (they shift out of energy mode into a cell protection response).

Research is now showing that these three things — the loss of mitochondria, the damage/dysfunction of mitochondria, and the shut down of mitochondria — are the primary factors that drive low energy levels.

In other words, if you’ve got low energy levels, it likely simply means that your mitochondria have become weak, damaged, dysfunctional, and switched off over time.

Here’s the spectrum of energy, so you can visualize where you are on this continuum.

Where are you on this spectrum?

If you’d like more energy, here’s what you need to know…

Supporting your mitochondrial health is the single most important thing you can do to help overcome fatigue and increase your energy levels.

There are 6 key pathways you need to build if you really want to build big healthy mitochondria that pump out energy all day long.

  • You Need BIGGER Mitochondria. Building the size of your mitochondria so they can produce more energy is one of the most important factors in increasing energy levels over time.
  • You Need MORE Mitochondria (i.e. Mitochondrial Biogenesis). The more mitochondria you have, the bigger your “cellular engine” grows, the more energy you’re able to produce. Several ingredients in this list can actually stimulate this process of mitochondrial biogenesis – allowing your body to build more mitochondria from scratch.
  • It’s VITAL to Repair and Protects Your Cell Membranes. Research has shown that one of the most potent ways to improve energy levels is to repair the physical membranes of your mitochondria. (Several of the ingredients on this list can do this, but #1 and #2 are especially powerful).
  • You Need Cofactors Involved Mitochondria Energy Production. These are substances that facilitate the process of mitochondria producing cellular energy.
  • You Need To Recharge NAD+ Levels. NAD+ is a critical regulator of mitochondrial energy production. Several key compounds in this list directly help rebuild our body’s supply of NAD+ (like #13, #20, #23, and #24).
  • You Need To Build Up Your Mitochondrial Internal Defense System (a.k.a. The NRF2 Pathway and the A.R.E.) People speak about the importance of antioxidants, but don’t realize that our cells’ internal antioxidant defense system is hundreds of times more powerful and more important. Several of the compounds in this list don’t just work as antioxidants, but even better, they build up the body’s internal cellular/mitochondrial antioxidant defense system — that makes our mitochondria more able to deal with stressors and protect themselves from damage, which ultimately means that instead of getting shut down, they stay in High Energy Mode pumping out energy.

Now that you understand all the background of how to build a REAL ENERGY at the cellular level, let’s get into the most powerful compounds for building your mitochondria and your energy levels!

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Energenesis: 1 Month Supply
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$119.00  $89.25

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*For international orders: All shipments are shipped Duties, Customs, & Taxes unpaid. Buyer is responsible for delivery fees.

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* For international orders: All shipments are shipped Duties, Customs, & Taxes unpaid. Buyer is responsible for delivery fees.

Energenesis Ingredients

What's Inside The Most Powerful Energy Supplement Ever Created

Mitochondrial Membrane Support Complex

NT Factor Phospholipids

This is one of the most powerful compounds for mitochondrial regeneration, probably the single most impressive individual supplement ever tested to help people overcome fatigue.

NTFactor® is a digestion-resistant phospholipid complex that supplies the materials necessary to repair and regenerate damaged cell membranes directly to mitochondria, a treatment called lipid replacement therapy [1].

By supplying the bioactive phospholipids that mitochondria require to naturally replace damaged membrane components, NTFactor® is able to regenerate dysfunctional mitochondria, increase energy production, and enhance the energy levels of those using it.

Numerous studies have shown that NTFactor® reduces fatigue by 24–43 percent among those with chronic fatigue syndrome or conditions associated with fatigue, like general aging, obesity, lyme disease, and Gulf War Illness [2]

In older adults, NTFactor® restored mitochondrial function to a level matching healthy 29 year-olds [3].

Astaxanthin

Astaxanthin is one of the most powerful membrane-specific antioxidants in existence. Not only is it 30–85 percent more potent than vitamin E and carotenoids like β-carotene, lycopene, and lutein [4], but it has a unique polar structure that allows it to cross through, protect, and stabilize the entire mitochondrial membrane [5].

Due to astaxanthin’s consistent and powerful ability to prevent oxidative damage and dysfunction to mitochondria [6–8], some researchers have even determined it to be “mitochondria-targeted antioxidant”[9].

Interventions have shown that astaxanthin supplementation increases muscular strength and power output in fatigued adults [10], enhances muscular endurance and recovery in recreational athletes [11,12], and reduces muscle damage and oxidative stress in elite soccer players [13].

Mitochondrial Energy Production Cofactor Complex

Acetyl-L-Carnitine

Acetyl-L-Carnitine (ALCAR) is a special form of carnitine that achieves two goals: (1) it supplies the carnitine your mitochondria need to produce energy, and (2) it provides an acetyl moiety that your mitochondria use to remain youthful and healthy.

The carnitine shuttle system is essential for bringing fatty acids into mitochondria to be used for energy production, and carnitine deficits (even mild ones) have been documented in those with chronic fatigue [14]. Moreover, over 20 percent of mitochondrial proteins rely on acetyl moieties to properly function, including those involved in antioxidant defenses and energy production [15,16].

For these reasons, some researchers have proposed that ALCAR should be considered a “mitochondrial rejuvenator” [17]. In chronically fatigued older adults, ALCAR supplementation led to profound benefits to their wellbeing — a 24 percent increase in physical function and close to a whopping 50 percent reduction in mental fatigue, physical fatigue, and overall fatigue severity [18].

D-Ribose

D-ribose is a naturally occurring sugar molecule that assists in the production of cellular energy by virtue of being a necessary component of ATP, DNA, and RNA [19]. In particular, it is the product of a rate-limiting step in ATP production within mitochondria and supplementation directly bypasses this bottleneck to increase energy production [20].

Studies show that D-ribose can help boost energy and physical function in situations where energy levels are reduced, such as people who have suffered from heart disease or stroke [21–23], or people engaging in regular intense exercise [24,25].

In adults with chronic fatigue, supplementing D-ribose led to 45 percent greater energy levels, 25 percent better sleep quality, 16% more mental clarity, 14 percent less pain, and 30% greater overall wellbeing [26]. Another study reported similar findings, with all benefits disappearing within a week of stopping supplementation [27].

Creatine Monohydrate

Creatine is a molecule necessary for rapid and explosive energy production when energy needs cannot be immediately met by our mitochondria. Supplementation works by increasing the amount of available creatine within our muscles.

This not only increases muscular performance, but also helps stimulate mitochondrial energy production when faced with signals to do so (like being physically active) [28], enhance mitochondrial biogenesis and integrity [29], and protect mitochondria from oxidative damage [30,31].

Accordingly, creatine is one of the most extensively researched supplements for improving exercise performance, muscle strength, and power output in people of all ages [32–36].

Magnesium

Magnesium is required for over 300 enzymes to function properly — muscle contractions, blood vessel regulation, insulin signaling, the synthesis of DNA and proteins, and nerve transmission all require magnesium [37].

One of the enzymes that relies on magnesium is ATP synthase, which is responsible for generating cellular energy (ATP) within mitochondria. Without magnesium, your mitochondria simply can’t function efficiently [38,39].

Energenesis provides two forms of magnesium, citrate and malate, which are both cofactors for mitochondrial energy production themselves.

Coenzyme Q10

Coenzyme Q10 (CoQ10) is an essential component of mitochondrial energy production, serving as both an antioxidant and an energy-transferring molecule. As such, deficits in CoQ10 will not only lead to a cessation of energy production, but also an increase in oxidative damage.

Individuals with chronic fatigue regularly show deficiencies in CoQ10 concentrations throughout the body [40], as do those with conditions in which fatigue is a common symptom, like fibromyalgia [41–43], those who have survived heart attacks or heart failure [44,45], and multiple sclerosis [46,47].

Supplementation with CoQ10 improves fatigue, autonomic nervous system activity (the part of the nervous system involved in rest and recovery), and biochemical parameters of mitochondrial energy production in those with chronic fatigue [48–51], and reduces general fatigue and oxidative stress in healthy adults [52,53].

Mitochondrial Energy Production Cofactor Complex

Green Tea Catechins

Green tea (Camellia Sinensis) catechins are four phytochemical molecules, the most potent one being epigallocatechin-3-gallate (EGCG). It has been implicated in benefiting almost every organ system in the body in doses you can obtain easily from simply drinking green tea [54–56].

EGCG is neuroprotective [57,58], cardioprotective [59,60], anti-obesity [61–63], anti-carcinogenic [64,65], and anti-diabetic [66], all due primarily to its ability to stimulate mitochondrial biogenesis, enhance energy production, and protect mitochondria from oxidative stress [67,68].

Supplementation of EGCG plus resveratrol (another ingredient of Energenesis) has been shown to significantly increase mitochondrial function and the use of fatty acids for energy production [69], and several meta-analyses have concluded that EGCG reduces body weight and body fat [70–73], particularly abdominal fat [74]. up> EGCG is neuroprotective, 155,156 cardioprotective, 157,158 anti-obesity, 159-161 anti-carcinogenic, 162,163 anti-diabetic, 164 and an overall powerful protector of your mitochondria. 165-167

In a 12-week double-blind trial published in the American Journal of Clinical Nutrition, researchers gave 38 overweight adults (ages 20 to 50) a daily polyphenol supplement or a placebo pill. The polyphenol supplement contained a mixture of EGCG (epigallocatechin-3-gallate, found in green tea) and resveratrol (which is also in Energenesis). People taking the polyphenol supplement had a highly significant increase in the function of mitochondria in their muscles compared to people given a placebo.

Pomegranate

Pomegranate is a rich source of ellagitannins, potent antioxidant molecules that can be further metabolized into other antioxidant derivatives like ellagic acid and urolithins [75,76].

Pomegranate ellagitannins and their derivatives have been shown to stimulate mitochondrial function [77], increase rates of mitophagy (a quality control pathway that helps remove damaged mitochondria) [78,79], and improve endurance exercise performance [80].

Moreover, pomegranate supplementation has been shown to reduce blood lipid oxidation and the accumulation of plaque in arteries [81], particularly in people who have higher levels of oxidative stress [82,83].

Panax Ginseng

Panax ginseng has been used medicinally for thousands of years in China, Korea, and Japan to alleviate physical and mental fatigue. While there are several types of ginseng on the market, panax ginseng is considered the “true” ginseng.

At a fundamental level, panax ginseng works to protect mitochondria from oxidative damage and improve energy production under conditions of oxidative stress [84,85]. A systematic review and meta-analysis of five studies in chronic fatigue patients found significant benefits of ginseng supplementation for reducing fatigue severity [86], with reductions of 20 percent after one month not being uncommon [87,88].

Ashwagandha

Ashwagandha (Withania somnifera) is a nightshade revered in Ayurvedic medicine for its physical- and mental-enhancing effects [89]. Today, it’s considered an adaptogen for similar reasons, able to increase a person’s resilience to stress and help reduce anxiety [90,91].

These effects are largely due to its constituent withanolide structures, which have several important neuroprotective effects within the brain, such as scavenging free radicals, reducing neuroinflammation, and promoting neurotransmitter signaling [92]. They also improve mitochondrial function and energy production [93].

In Energenesis, we use the most potent form of ashwagandha, a 35% withanolide concentrate called the Shoden extract, which reduces stress by 30% in mildly stressed adults at less than half the dose used with other extracts [94].

Other studies using the KSM-66 extract (5% withanolides) have shown supplementation to reduce perceived stress by 15–20 percent in mildly stressed healthy adults [95,96], 40–70 percent in adults battling chronic mental stress [97], and 50 percent in adults with an anxiety disorder [98].

Alpha-Lipoic Acid (ideally R-ALA)

Alpha-lipoic acid (ALA) is a mitochondrial molecule involved in energy metabolism and the antioxidant system. It is not only essential for mitochondria to create cellular energy, but also serves to function as an antioxidant, replenish other antioxidants, and stimulate the production of antioxidant enzymes like glutathione [99].

Accordingly, ALA has been heavily investigated as a mitochondrial rejunivator, able to help reverse age-related declines in mitochondrial energy production [100], particularly within the brian [101,102].

By improving mitochondrial function and protecting against oxidative stress, ALA has been shown to benefit metabolic health [103,104], as well as facilitate weight loss among those who are overweight [105–107].

ALA exists as either an S or R isomer, with unspecified ALA being a 50-50 ‘racemic’ solution of both. Most studies use the racemic solution, but only R-ALA has biological activity in the body and is more bioavailable [108], which is why we use it in Energenesis.

PQQ (Pyrroloquinoline Quinone)

Pyrroloquinoline Quinone (PQQ) is a potent stimulator of pathways involved in mitochondrial biogenesis and antioxidant defenses [109,110]. In particular, it stimulates pathways shared by exercise training and is believed to potentiate and enhance activity-induced benefits on mitochondria [111].

Supplementation has been shown to reduce fatigue and increase vigor by 20 percent in adults complaining of poor sleep and energy levels, as well as improve mood, sleep quality, and overall quality of life [112]. In another study of healthy adults, PQQ reduced inflammation and improved markers of mitochondrial respiration [113].

NAD+ Regeneration Complex

Taurine

Taurine is an omnipresent amino acid within the body, essential for the development and function of our cardiovascular, muscular, nervous, and ocular systems [114]. It’s also essential for mitochondrial energy production and protein synthesis [115,116]

The highest amounts of taurine are in tissues with huge energy requirements and a lot of mitochondria, such as the retina, nerves, kidney, heart, and skeletal muscle [117]. If mitochondria don’t have enough taurine, energy production decreases and oxidative stress increases [118].

Insufficient taurine has been implicated in numerous chronic disease states [119,120], and several clinical trials have shown that supplementing with taurine reduces oxidative stress and inflammation in those with metabolic dysfunction [121–123].

Additionally, a meta-analysis reported that taurine supplementation improved endurance exercise performance, particularly power output and the amount of time that people could run before exhaustion [124].

Citrus Bioflavonoids (Hesperidin, Rutin, Naringenin

Citrus bioflavonoids are a group of molecules, particularly hesperidin, naringenin, and rutin, which have potent antioxidant and anti-inflammatory effects within the body [125]. They also increase mitochondrial energy production, biogenesis, and mitophagy [126–129].

Supplementation has been shown to increase sprint performance, power output, and exercise economy (requiring less energy to generate a given power output) in athletes [130,131].

Quercetin

Quercetin is a potent antioxidant and anti-inflammatory molecule that affects an array of mitochondrial processes, including mitochondrial biogenesis, mitochondrial energy production, and the protection of mitochondria from oxidative stress [138,139].

Several meta-analyses of clinical trials have reported that quercetin is able to improve endurance exercise performance and maximal oxygen consumption [140,141], and, in those with metabolic dysfunction, reduce markers of inflammation [142,143], improve blood lipids [144–146], and lower blood pressure [147,148].

Importantly, these all use regular unenhanced quercetin. Yet, a quercetin phytosome complex has vastly superior bioavailability, leading to quercetin levels 20-fold greater in the blood following supplementation [149], which is why we use this form in Energenesis.

Resveratrol (ideally Trans-Resveratrol)

Resveratrol is a phytochemical found primarily in grape skins and wine. It works primarily through hormesis [132]; it stresses our mitochondria and stimulates adaptations that ultimately make them bigger and stronger [133].

Supplementation has been shown to activate several mitochondrial regulators, including AMPK, SIRT1, and PGC-1α, while also increasing the ability of mitochondria to oxidize fat as an energy source [134,135]. Resveratrol also increases mitochondrial adaptations to exercise more than exercise alone would [136,137].

N-Acetyl Cysteine (NAC)

N-Acetyl-Cysteine (NAC) is a molecule our body naturally creates from the amino acid cysteine as a precursor to one of our body’s master antioxidants, glutathione, which is not only a potent antioxidant, but a molecule required to recycle other antioxidants, detoxify and excrete toxins, and maintain mitochondrial function [150].

Supplemental NAC is an effective way at increasing glutathione concentrations in our body [151,152], and a meta-analysis of 28 clinical trials found that NAC supplementation significantly reduced biomarkers of oxidative stress and inflammation [153].

Through helping to sustain optimal glutathione concentrations, NAC has been demonstrated to reduce mitochondrial oxidative damage and preserve cellular life in the face of genetic mitochondrial mutations that cause dysfunction or toxic conditions that directly damage mitochondria [154–157].

B3 Variants (NMN, NR, Niacin & Niacinamide)

Niacin is an essential component of energy-carrying molecules within the mitochondria, all of which are derivatives of nicotinamide adenine dinucleotide (NAD+). NAD+ is important for energy production, mitochondrial function, and cellular repair processes.

The primary route of NAD+ synthesis is through something called the salvage pathway, in which niacinamide serves as the starting molecule. We can also make NAD+ from nicotinic acid using an alternative pathway, which is why we’ve included both forms in Energenesis to ensure that NAD+ generation is not being impeded by a simple vitamin insufficiency.

Transparency on the Label

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Energenesis: 1 Month Supply
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$119.00  $89.25

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*For international orders: All shipments are shipped Duties, Customs, & Taxes unpaid. Buyer is responsible for delivery fees.

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What people say about Energenesis

I am a 72 year old female and I love, love, love Energensis. I have more sustained energy throughout the day and am actually getting my life back. I am doing things that haven't been able to do for 10 years. I also seem to have a much better attitude about life, my day, whatever."

Barbara F.

Just wanted to say I am absolutely blown away with Energenesis. Have had it for a couple weeks now, and my energy levels are already starting to feel like they were when I was a kid."

Kyle T.

The reason I'm writing is to thank you for Energenesis! I've just taken it a few times, but I'm already amazed by my increased energy & focus levels. This stuff is amazing...

Tyler Y.

Energenesis gave me my life back."

Denise P.

Introducing The Most Powerful Mitochondria and Energy Support Supplement Ever Created - Energenesis

I’m excited to announce that after nearly 2 years of development, my team and I have developed the most powerful mitochondrial energy supplement ever developed.

I say this definitively, because once you see the list of ingredients in this (it includes almost all the ingredients mentioned in the list above) and the fact that it has REAL effective doses of these ingredients (which no other manufacturer is doing), you’re going to be blown away…

Energenesis is the most powerful mitochondria-enhancing nutraceutical ever created!

Energenesis is the first non-stimulant energy formula that actually builds up your own body’s ability to produce energy!

Packed with a potent dose of a whopping 23 of the most powerful mitochondria-building ingredients in existence, Energenesis is a NEW, premium, scientifically-backed formula to re-awaken your body’s built-in energy system.

What makes Energenesis different?

Unlike previous generation “energy supplements,” it contains no stimulants, no caffeine, and no sugar. This isn’t about giving you a fake energy boost, while actually making your energy levels worse over time.

Energenesis builds REAL ENERGY!

This is not a supplement designed to fill to people’s desire for quick fixes and instant gratification through stimulants and temporary boosts of fake energy.

Energenesis is for people looking for REAL ANSWERS, who want to address ROOT CAUSES, and want to build real energy at the cellular level.

As a result, the energy your mitochondria produce naturally decreases over time, reducing your health and longevity — and ultimately, causing fatigue.

On top of that, stressors in our life — from psychological stress, to environmental toxins (like heavy metals and air pollutants), to a poor diet, to poor gut health, to chronic inflammation — all cause mitochondrial damage, dysfunction and shut down (they shift out of energy mode into a cell protection response).

Research is now showing that these three things — the loss of mitochondria, the damage/dysfunction of mitochondria, and the shut down of mitochondria — are the primary factors that drive low energy levels.

In other words, if you’ve got low energy levels, it likely simply means that your mitochondria have become weak, damaged, dysfunctional, and switched off over time.

Here’s the spectrum of energy, so you can visualize where you are on this continuum.

As you take Energenesis consistently over several weeks, it builds up your cellular engine, your mitochondria.

You may feel a slight energy boost from the very first time you take it, but what it’s really doing is steadily and sustainably re-charging and building up your mitochondria so that your body becomes capable of producing more energy on its own!

In short, Energenesis is a repair system for the natural process of dysfunctional energy producing cells. It acts by restoring your body’s ability to rely on itself for energy.

The old way to make an energy supplement was just about using caffeine, sugar and other stimulants to give a quick jolt. (While actually making you worse over time.)

We’re here to introduce the NEW way to make an energy supplement – by using the science of how to actually build up the body’s own production of cellular energy!

The Difference Between Caffeine/Stimulant "Energy" Supplements vs. Energenesis

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Energenesis: 1 Month Supply
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Energenesis is a next generation energy supplement

Remember the 6 key mechanisms you need to support optimal mitochondrial health:

  1. You need BIGGER Mitochondria
  2. You Need MORE Mitochondria (i.e. Mitochondrial Biogenesis)
  3. It’s VITAL to Repair and Protect Your Mitochondrial Membranes
  4. You NEED Cofactors Involved Mitochondrial Energy Production
  5. You Need to Recharge NAD+ Levels
  6. You Need to Build Up Your Mitochondrial Internal Defense System

This is EXACTLY what Energenesis is designed to do!

What's in Energenesis?

Energenesis is like a 5-star MEAL for your Mitochondria (LOADED with rare nutrients, energy boosters and powerful antioxidants, because your body needs a variety – each one works differently!) AND… we have gone to amazing lengths to source the highest quality ingredients, with unparalleled potency, purity, biological availability, and effectiveness…

If you want to see a breakdown of the exact ingredients and amounts, you can look in the right column of the image below…

It’s a potent cocktail of the most powerful mitochondrial regenerating ingredients designed to literally CHARGE your cells back up, so you can have the energy you had when you were young – ALL DAY ENERGY.

If you’ve been struggling with fatigue or low energy levels, it’s time to stop dragging yourself through the day with caffeine and stimulants…

It’s time to start building REAL ENERGY.

You can certainly use the information here to go out and buy all these compounds as separate supplements, but I strongly encourage you to simply get Energenesis. It’s obviously far more convenient to get everything in one formula rather than fiddling with 20 different bottles and 25 pills each day. Also, you don’t have to worry about dosing everything correctly.

And, on top of that, I’ve tried to make it a complete no brainer for you by making it way cheaper for you to order it this way (as opposed to buying 20+ different supplements).

Energenesis is simply the most powerful formula ever developed for that purpose.

We have it available in either 1, 3, or 5 bottle packages (obviously, the more you order, the cheaper it gets).

What people say about Energenesis

Energenesis has brought me to a higher level of competition this year in bike racing. I've been able to race again some really fast men and beat some of them...going to nationals in a few weeks since I'm feeling so good!"

Bonnie S.

I feel a definite improvement in my energy, mood, and even sleep, and also my capacity at the gym..."

Getty P.

...my brain fog has lifted."

Mary Ann C.

...loved it immediately. My energy was better and sustained throughout day and I look forward to it in the morning!"

Raquel F.

Decrease Brain Fog, and Improve Brain Energy, Focus, And Memory

Supercharge Your Mitochondria

Increase Your Physical Energy Levels

Energenesis

Enhance Your Stamina & Endurance

Improve Your Mood

Improve Your Brain Function & Focus

Get Your Energenesis Now!

Energenesis: 1 Month Supply
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Energenesis: 3 Month Supply
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$119.00  $89.25

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References

1. Nicolson GL, Ash ME. Lipid Replacement Therapy: a natural medicine approach to replacing damaged lipids in cellular membranes and organelles and restoring function. Biochim Biophys Acta. 2014;1838:1657–79.

2. Nicolson GL, Rosenblatt S, de Mattos GF, Settineri R, Breeding PC, Ellithorpe RR, et al. Clinical Uses of Membrane Lipid Replacement Supplements in Restoring Membrane Function and Reducing Fatigue in Chronic Diseases and Cancer. Discoveries (Craiova). 2016;4:e54.

3. Agadjanyan M, Vasilevko V, Ghochikyan A, Berns P, Kesslak P, Settineri RA, et al. Nutritional Supplement (NT FactorTM) Restores Mitochondrial Function and Reduces Moderately Severe Fatigue in Aged Subjects. J Chronic Fatigue Syndr. Taylor & Francis; 2003;11:23–36.

4. Naguib YM. Antioxidant activities of astaxanthin and related carotenoids. J Agric Food Chem. 2000;48:1150–4.

5. Kidd P. Astaxanthin,cell membrane nutrient with diverse clinical benefits and anti-aging potential. Altern Med Rev. 2011;16:355–64.

6. Kim SH, Kim H. Inhibitory Effect of Astaxanthin on Oxidative Stress-Induced Mitochondrial Dysfunction-A Mini-Review. Nutrients [Internet]. 2018;10. Available from: http://dx.doi.org/10.3390/nu10091137

7. Yu T, Dohl J, Chen Y, Gasier HG, Deuster PA. Astaxanthin but not quercetin preserves mitochondrial integrity and function, ameliorates oxidative stress, and reduces heat-induced skeletal muscle injury. J Cell Physiol. 2019;234:13292–302.

8. Krestinina O, Baburina Y, Krestinin R, Odinokova I, Fadeeva I, Sotnikova L. Astaxanthin Prevents Mitochondrial Impairment Induced by Isoproterenol in Isolated Rat Heart Mitochondria. Antioxidants (Basel) [Internet]. 2020;9. Available from: http://dx.doi.org/10.3390/antiox9030262

9. Sztretye M, Dienes B, Gönczi M, Czirják T, Csernoch L, Dux L, et al. Astaxanthin: A Potential Mitochondrial-Targeted Antioxidant Treatment in Diseases and with Aging. Oxid Med Cell Longev. 2019;2019:3849692.

10. Liu SZ, Ali AS, Campbell MD, Kilroy K, Shankland EG, Roshanravan B, et al. Building strength, endurance, and mobility using an astaxanthin formulation with functional training in elderly. J Cachexia Sarcopenia Muscle. 2018;9:826–33.

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